New issue, I'm hoping it is now resolved. I'd be playing a game (Path of Exile), and I'd suddenly lose control of the mouse, get a bump on my latency, and hear a sound like a device being unplugged, just for a second, and then control would come back. I've moved the mouse to a new port on the back where it might have less strain on the cord, and manually set the monitor to use the Display Port. If that doesn't work, I'll try a different mouse.