Took the red pill.
Not really one thing, but so many individual things that always helped.
Ditched a superficial girlfriend only to end up with an amazing partner
Left a great office job and chose to work outside for something that made me happy
Sold the car and started riding
Stopped smoking cigarettes and took up running
Gave up eating meat and started growing my own veggies
Sold the condo and got a house with all I could ever want
Work less and volunteer more
26 years ago moved to Canada for work even though I knew nobody here at all.