Big family, we've owned a number of Honda's..
88 Honda Civic - 330,000+ kms (sold)
96 Honda Civic - 260,000 kms (sold)
06 Honda Civic - 280,000 kms (still running)
06 Honda Odyssey - 84,000 kms (leased, returned)
06 Honda Accord v6 - 85,0000 kms (leased, returned)
10 Honda Odyssey - 70,000 kms (leased, current)
10 Honda Crosstour - 55,000 kms (leased, current)
2001 Honda CBR600F4i 30,000 kms (street bike, sold)
2002 Honda CBR600F4i 35,000 kms (track bike, sold)
2008 Honda CBR600RR 25,000 kms (current)
2008 EU2000 Generator, runs like new
2007 HS520A Snow Blower, runs like new
I might be lucky, but all of the Honda's we've owned have been fantastic machines. I've owned a Suzuki, three Ducati's, two Kawasaki's, two Yamaha's including my current 2009 R6 track bike, and a ton of American vehicles. My wife rides a Vespa (after me spending significant time getting it to run smoothly). Some have been decent, others complete duds, but none have been as reliable as Honda.
Your mileage may vary of course, but any other choice is a hard sell for me given my personal experience.