One day would be a stretch with the shorter daylight hours and you could miss peak colour in October - the mountains turn earlier. Northern PA might be a better bet - or Finger Lakes region has beautiful fall foliage as well and turns later in the year, but not very exciting roads. Same around Ellicotville and other upstate NY areas.
We are probably going to hit the best foliage of the year in Algonquin this weekend.
Shoot ya know what... algonquin might be a better plan actually! Gotta map a good route now... thanks!
You can always just join up for the Algonquin Park ride this weekend on Sunday! Unless you prefer solo, then just follow the route. I did that last year because I couldn't make the group ride, so I went the week after with a member from here and just followed the same route anyway.