I feel the Tuono is the better of the V60 twins, personally. But if you haven't tried the RSV4 yet, you really can't compare... it feels so different from a Japanese bike of any measure and is so much more "alive" than most bikes you could mention, it almost doesn't feel like the same thing. When you ride a RSV4, you're riding a machine - which feels carved out of steel - that constantly lets you know what it's doing and that it is, indeed, meant for going as fast as you have the guts to take it. Hard to explain, but it really does feel more like a race bike than my race bikes do. And it is *not* cramped for a 6'+ rider. It is physically small, however.
The new Tuono really has me gobsmacked. I just love my V60 too much to sell/trade it right yet... I'm thinking that another year is needed in my stable. BTW, i've heard that most of the incoming Tuono V4Rs into Canada are pre-sold and they will all arrive with the APRC package, no standard bike available. All speculation but I heard it from two dealers...
BTW, I do have one complaint about the RSV4, which is that it is hot. Really hot. However it's a relatively minor complaint, and frankly I found the 2010 R1 to be much hotter and in a less welcome place.