Beachguy...
The city performance on the KLR650 and the Burgman will be with a nod to the Burgman and the ease of handling in the city plus storage goes a long way in the Burgman's favor.
I love my Honda ST1100 in Australia on the open road - it's a pig in the city especially in the heat and I"ll take the KLR650 to the pool or the forest tracks.
For here tho the Burgman 650 is the best all around bike I"ve owned but for the price and the use the 400 would be better.
Don't let the anti-scoot snobs steer you off.
http://burgmanusa.com/forums/
There are thousands of Burgman riders in North America and in Europe the big scoots are counted in the 10s of thousands and most of those are for city use with the occasional jaunt on the highway which it will handle fine.
Motorcycles are severely outnumbered in the cities...
I took this shot in Barcelona this year
and I'd guess it's about 1:1 cars to scoots with a high percentage of the big ones.
With the CVTs you will not miss acceleration in the city they are quick, just roll and go.- no chain to oil - loads of space under the seat for errands or jacket and helmet.-
If part of the goal is say wandering dirt roads then the KLR is the ticket and that one is a nice mix for city plus the custom stuff sure has "character".
The upright seating is a treat. As long as you are tall enough to flat foot - it's an easy bike to ride and those custom boxes are a hoot.
If you were buying new I'd say give the new CB500x a look....brilliant offering from Honda and exactly what you are looking for. Amazing machine for the money - total fun, super light and effortless to handle.
Good luck - good time of year to snag something.
I ride the 650 Burgman 9 months - the upfront protection is superb. The rest of the year I ride the other two in Australia