I have ridden this state from top to bottom east to west and my recomendation would be buy an old fashioned Rand and Mcnally road atlas. Must be a Rand and Mcnally, they are extremely accurate and will show what roads are twisty, interesting etc. Once south of NY you really don't have to worry about road conditions that much, so pick the most interesting paved roads for you and let it rip. Sometimes the old fashioned way isn't the sexiest but the most accurate. Get the atlas and put your feet up and spend sometime just relaxing and viewing the roads available. There is however one potential fly in the ointment, as a previous poster mentioned, there is a great deal of "fracking" in north central Penn. this leads to a lot of truck traffic sometimes in places you wouldn't expect it. As an example along Hwy #6 in the north central areas. usually you can avoid it but keep an eye open for it, but the real downer is that a lot of these "frackers" are from outside the state Texas,Oklahoma etc. and they stay in motels, so a lot of your typical Super 8 style motels may be full up with these guys, just phone ahead to confirm if there is any vacancy at a motel you might want to stay at. Typically there will be room, but just not as many available rooms because of these out of state "frackers". Have fun, I'll be down there a few times this year as well.